It regulates the activity of the immune system, which may be overactive in some conditions. Hydroxychloroquine can modify the underlying disease process, rather than simply treating the symptoms. Hydroxychloroquine does Took plaquenil during pregnancy Chloroquine family My question is for those that have taken Plaquenil/Hydroxychloroquine. How long did it take for it to remove symptoms in your personal experience? I know I've read it can take up to 6 months but what I'm wondering is, do you just wake up one day and find it's kicked in 6 months down the road or more likely, it starts to work slowly over 6 months? I am so sick of meds but I need them. Generic plaquenil does not work for me. Rips my stomach apart and leaves me with no apetite. My pharm keeps changing manufacturers and it seems like every different one has a new side effect. Before taking plaquenil I was taking Quinicrine which is a compound for 11 years. Hydroxychloroquine is a DMARD. The brand name is Plaquenil. What does Plaquenil do? Plaquenil relieves pain and swelling and prevents damage to joints. How long does Plaquenil take to work? Plaquenil works very slowly. In 1 to 3 months you should start to feel better. You may continue to get better for up to 1 year. Hydroxychloroquine is often taken in combination with other drugs such as methotrexate. Over the long term hydroxychloroquine can reduce pain, swelling and joint stiffness. It may be as long as 12 weeks before you notice the benefits. Why does plaquenil take so long to work Hydroxychloroquine Plaquenil -, Study Raises Questions about Sjogren's and Plaquenil Sulfasalazine taken with hydroxychloroquineLog p chloroquinePlaquenil back pain and headacheWhat is the mechanism of action of chloroquine and primaquinePlaquenil derived from Kids shouldn't take Plaquenil as a long-term treatment. Overdose can be fatal in children. So you should keep Plaquenil out of their reach. Plaquenil and Eye Problems. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Lupus Medicines Hydroxychloroquine - Brigham and Women's.. PLAQUENIL Side Effects, Reviews by Patients -. How long does it take for plaquenil to work? Unanswered Questions. 1. Why was it once illegal to eat ice cream on cherry pie in Kansas. 2. Why do work permits in the us take so long? Long term ratings 2.8/5. This is a reivew of how effective Plaquenil hydroxychloroquine sulfate is for Sarcoidosis and for what kind of people. The study is created by eHealthMe from 9 Plaquenil users and is updated continuously. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria.