Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Screening criteria for ocular toxicity of plaquenil Antipaludéen de synthèse plaquenil If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. Plaquenil may interact with Cymbalta and may reduce the effectiveness of methotrexate. Magnesium should also be taken 4 hours apart because it also affects the way the body absorbs the Plaquenil. It can also affect the body's vitamin d levels. Taking B6 with Plaquenil can get rid of skin nodules associated with RA. No treatment to reverse chloroquine or hydroxychloroquine toxicity. Recommend cessation of the medication, but visual function rarely recovers, especially in the later stages of the disease. Continued deterioration in visual function can occur for a year after discontinuing hydroxychloroquine, possibly due to slow clearance of the medication from the retina and body. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. How to reverse the side gastrointestinal side effects of plaquenil Plaquenil - Side Effects, Uses, Dosage, Overdose, Pregnancy., Starting Plaquenil DailyStrength What if you take double the dosage of plaquenil Sep 13, 2019 Some side effects of hydroxychloroquine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Hydroxychloroquine Side Effects -. Hydroxychloroquine Plaquenil Toxicity and.. Plaquenil Side Effects Common, Severe, Long Term -. Check with your doctor immediately if any of the following side effects occur Incidence not known. Blistering, peeling, loosening of the skin blurred vision or other vision changes chest discomfort, pain, or tightness cough or hoarseness dark urine decreased urination defective color vision diarrhea difficulty breathing Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. That said, my doctor had originally prescribed for me to take 100mg/day for one week and then increase to 200mg/day. When I increased to 200mg/day, I had strange side effects that caused me to go back to 100/day. Strange leg cramping, restless leg, nausea and anxiety. In a nutshell, at 200mg/day the side effects outweighed the benefits.