Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Itp plaquenil Substitute for hydroxychloroquine Plaquenil success stories Plaquenil primary biliary cirrhosis Oct 04, 2011 Hydroxychloroquine Plaquenil is used to treat malaria, lupus and rheumatoid arthritis. It is a known retinal toxin, and the effects are irreversible. Fortunately, most patients taking this drug do not experience side effects at the dosages usually prescribed. Cessation of the drug is the only effective management of the toxicity. CONCLUSION Consensus with regard to various important aspects of hydroxychloroquine ocular toxicity is limited, especially. Hydroxychloroquine can cause ocular toxicity, with the most serious being an irreversible retinopathy. At the present time, no "gold standard" exists for identification of the ocular toxicity. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Ocular toxicity hydroxychloroquine Plaquenil Side Effects on Your Eyes and Vision, Ocular toxicity of hydroxychloroquine. Hydroxychloroquine dose for lichen planopialrisChloroquine proguanil antimalarialHydroxychloroquine pn singlecareCan plaquenil affect your thyroid Hydroxychloroquine ocular toxicity includes keratopathy, ciliary body involvement, lens opacities, and retinopathy. Retinopathy is the major concern others are more common but benign. The incidence of true hydroxychloroquine retinopathy is exceedingly low; less than 50 cases have been reported. Although its pathogenesis is unclear, risk. Ocular toxicity of hydroxychloroquine HKMJ. Ocular Toxicity of Hydroxychloroquine Request PDF. The Risk of Retinal Toxicity with Plaquenil. WAIKOLOA, Hawaii — Hydroxychloroquine is used extensively by rheumatologists and dermatologists and yields little systemic concerns, but ophthalmologists are well aware of the bull’s eye type. Clinical research has resulted in precise screening protocols and safe dosing guidelines to prevent ocular toxicity and detect retinal damage at an early stage. Etiology Chloroquine and hydroxychloroquine bind to melanin in the retinal pigment epithelium RPE and cause damage to the macular cones outside of the fovea. Hydroxychloroquine sulfate HCQ, Plaquenil is an analogue of chloroquine CQ, an antimalarial agent, used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune disorders. Its use has been associated with severe retinal toxicity, requiring a discontinuation of therapy.