So far I have no more energy than when I first started and has developed neuropathy which I have just found out from Web MD that this neuropathy is one of the side effects of this med! Saying that by stopping this it would take another 6 months to build up the benefit. There are other meds that can help with what you are experiencing, and if your doctor didn't address that then I would seek out a second opinion... Please don't stop your plaquenil until you are sure it is the right thing to do and in your best interest. Drug interactions with hydroxychloroquine Plaquenil live vaccines I recently decided to stop taking Plaquenil because I was having constant chest pains even more so than I usually have due to Lupus. Since I have not taken it my chest feels so much better which is odd because chest pain is not listed as a side effect. Also I noticed that the Plaquenil I think was making me feel different but not in a good way. May 13, 2009 The OR of pre-mature birth defined as birth before 37 weeks in women taking HCQ during pregnancy was 1.10 95% CI 0.75, 1.61. Conclusion HCQ is not associated with any increased risk of congenital defects, spontaneous abortions, fetal death, pre-maturity and decreased numbers of live births in patients with auto-immune diseases. Saturday was a week since I stopped taking Plaquenil, aka Hydroxychloroquine, per my doctor's instructions, and I think I am going through some form of withdrawal. I took the drug as a treatment for sarcoidosis and one of the side effects is a reduction in white blood cells, which is what has happened to me. Plaquenil Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. Or maybe another doctor if you're not comfortable w/your current one. Stopping plaquenil before pregnancy Hydroxychloroquine HCQ for Recurrent Pregnancy Loss., Systematic review of hydroxychloroquine use in pregnant. Hypnozoite chloroquine resistanceChloroquine and p62 No fetal abnormalities are known to have occurred from taking hydroxychloroquine, and physicians at several major universities have used anti-malarial drugs for years to treat pregnant women with lupus without negative side effects on the fetus. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. Plaquenil Withdrawal – Life As An Anomaly. Hydroxychloroquine Plaquenil. Nov 12, 2009 Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. If you're gonna experiment, I went off it cold turkey as it didn't hurt to do it that way, but you better get back on before the summer or you could experience a flare-up. The simple answer is to stop all unnecessary medications before attempting pregnancy, but of course, that's not always possible. Some that you should definitely avoid because they can harm the fetus include isotretinoin, better known as Accutane for acne. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.