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    Duloxetin ist ein Arzneistoff aus der Gruppe der selektiven Serotonin-Noradrenalin-Wiederaufnahmehemmer (SSNRI) und wird in der Behandlung von Depressionen, generalisierten Angststörungen, diabetischer Polyneuropathie und Harninkontinenz eingesetzt. In den Studien wurden neben den psychischen Beschwerden auch begleitende körperliche Symptome (zum Beispiel Schmerzen) gelindert. Der analgetische Effekt bei Schmerzsymptomen in Verbindung mit Depression ist nach einer neueren Metaanalyse vorhanden, allerdings sehr gering ausgeprägt. Duloxetin hat im Verhältnis zum Nutzen deutlich höhere Preise als andere Antidepressiva. So lautet der Befund der ersten Kosten-Nutzen-Bewertung des Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWi G) für die Wirkstoffe Venlafaxin, Duloxetin, Bupropion und Mirtazapin. European Public Assessment Reports (EPARs) zu allen Produkten: siehe Weblinks. August 2004 erteilte die Europäische Kommission dem Unternehmen Eli Lilly Nederland B. eine Genehmigung für das Inverkehrbringen von Yentreve in der gesamten Europäischen Union. Entgegen den Erwartungen der Partner (Eli Lilly und Boehringer Ingelheim) verlief der Umsatz von Yentreve enttäuschend, woraufhin sich Boehringer Ingelheim aus der gemeinsamen Kooperation mit Lilly im Bereich Belastungsinkontinenz verabschiedete. Im Januar 2005 wurde in den USA der Zulassungsantrag für Yentreve hingegen zurückgezogen, da die FDA schwere Sicherheitsbedenken hatte. Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor antidepressant (SSNRI). Duloxetine affects chemicals in the brain that may be unbalanced in people with depression. Duloxetine is used to treat major depressive disorder in adults. It is also used to treat general anxiety disorder in adults and children who are at least 7 years old. Duloxetine is also used in adults to treat fibromyalgia (a chronic pain disorder), or chronic muscle or joint pain (such as low back pain and osteoarthritis pain). Duloxetine is also used to treat pain caused by nerve damage in adults with diabetes (diabetic neuropathy). Do not take duloxetine within 5 days before or 14 days after you have used an MAO inhibitor, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine. Some young people have thoughts about suicide when first taking an antidepressant. Report any new or worsening symptoms to your doctor.

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    Duloxetine 30mg Gastro-resistant Capsules, hard. 2. Qualitative and quantitative composition. Each capsule contains 30 mg of duloxetine as hydrochloride. Duloxetine, sold under the brand name Cymbalta among others, is a medication used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, and. Duloxetine oral capsule is a prescription medication used to treat depression, anxiety, diabetes nerve pain, fibromyalgia, and chronic pain. It's available.

    Antidepressant medications are used to treat a variety of conditions, including depression and other mental/mood disorders. These medications can help prevent suicidal thoughts/attempts and provide other important benefits. However, a small number of people (especially people younger than 25) who take antidepressants for any condition may experience worsening depression, other mental/mood symptoms, or suicidal thoughts/attempts. Therefore, it is very important to talk with the doctor about the risks and benefits of antidepressant medication (especially for people younger than 25), even if treatment is not for a mental/mood condition. Tell the doctor right away if you notice worsening depression/other psychiatric conditions, unusual behavior changes (including possible suicidal thoughts/attempts), or other mental/mood changes (including new/worsening anxiety, panic attacks, trouble sleeping, irritability, hostile/angry feelings, impulsive actions, severe restlessness, very rapid speech). Be especially watchful for these symptoms when a new antidepressant is started or when the dose is changed. Show More Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). In some cases, they may not be available in all strengths or forms as the brand-name drug. Duloxetine oral capsule is available as the brand-name drugs Cymbalta and Irenka. Generic drugs usually cost less than the brand-name version. Duloxetine oral capsule is used to treat: Duloxetine belongs to a class of drugs called serotonin-norepinephrine reuptake inhibitors (SNRIs). It works by balancing chemicals in your brain that cause depression and anxiety. By balancing these chemicals, this drug also helps inhibit pain signals from your nerves to your brain. Duloxetine oral capsule can cause sleepiness or may affect your ability to make decisions, think clearly, or react quickly. You shouldn’t drive, use heavy machinery, or do other dangerous activities until you know how it affects you. In adults, the more common side effects of duloxetine can include: Call your doctor right away if you have serious side effects.

    Duloxetine hcl 30mg

    Duloxetine Oral Uses, Side Effects, Interactions, Pictures, Warnings., Duloxetine - Wikipedia

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    Pictures of Cymbalta Duloxetine Hcl, drug imprint information, side effects for the patient. Compare prices, print coupons and get savings tips for Duloxetine Generic Cymbalta and other Anxiety, Depression, Diabetic Neuropathy, Fibromyalgia, and. Duloxetine Hydrochloride, Capsule, delayed release, 30 mg/1, Oral, Lake Erie Medical Dba Quality Care Produts Llc, 2014-06-13, Not applicable, US Us.

     
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    Accepted for publication 17 February 2017 Published Volume 20 Pages 1481—1488 DOI https://doi.org/10.2147/DDDT. S131670 Checked for plagiarism Yes Review by Single-blind Peer reviewers approved by Dr Rasika Samarasinghe Peer reviewer comments 2 Editor who approved publication: Professor Manfred Ogris Ph D School in Experimental Medicine, University of Pavia, Pavia, Italy Purpose: The purpose of this study is to evaluate, in a randomized clinical trial, the effects of metformin immediate release (IR) compared with metformin extended release (XR) on the gastrointestinal tolerability and glycemic control. Materials and methods: We enrolled 253 Caucasian patients with type 2 diabetes not well controlled by diet (glycated hemoglobin [Hb A, fasting and postprandial glucose, fasting plasma insulin (FPI) and homeostasis model assessment insulin resistance (HOMA-IR), lipid profile, and levels of some adipocytokines, including tumor necrosis factor-α (TNF-α), high-sensitivity C-reactive protein (hs-CRP), visfatin, and vaspin. Moreover, at the baseline and after 6 months, we administered patients some validated questionnaires to assess patients’ satisfaction toward treatments. Results: After 6 months, both formulations gave a similar reduction in body weight and body mass index (BMI); however, metformin XR gave a greater improvement in glycemic control, FPI, and HOMA-IR, compared with both baseline and metformin IR. A reduction in total cholesterol (TC) and low-density lipoprotein (LDL) cholesterol was observed with metformin XR compared with IR. Levels of TNF-α, hs-CRP, and vaspin were reduced by metformin XR but not by the IR formulation. Conclusion: Metformin XR formulation seems to be more effective than metformin IR in improving glyco-metabolic control, lipid profile, and levels of some adipocytokines in patients with type 2 diabetes mellitus. Metformin Extended-Release Tablets Information - Advantages of extended-release metformin in patients with type 2. Metformin Side Effects, Dosage, Uses, and More - Healthline
     
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