B, Brown pigmentation on the legs in another patient who had systemic lupus erythematosus associated with diffuse discoid lupus. The skin biopsy was performed on the brown area distant from discoid lesions. Retina doctors westport ct plaquenil Apple cider vinegar interaction with hydroxychloroquine Chloroquine purpose blood bank Plaquenil dose for rheumatoid arthritis We study how severe was Skin discoloration - bluish, when it was recovered, drug effectiveness, race, and more among people who take Plaquenil and have side effects - Discoid lupus lesions are often red, scaly, and thick. Usually they do not hurt or itch. Over time, these lesions can produce scarring and skin discoloration darkly colored and/or lightly colored areas. Discoid lesions that occur on the scalp may cause the hair to fall out. If the lesions form scars when they heal, the hair loss may be permanent. For the first month I was on Plaquenil my hand and lower arms and lower legs were itchy and had some of the little blisters, my skin got discolored and I had little weird pains in my skin of my lower legs. After about a month it all stopped except the light brown discoloration stayed. B, Presence of iron in the same areas of the dermis (Perls staining, original magnification ×100). Pub Med Google Scholar Crossref Morrison LK, Nordlund JJ, Heffernan MP. Pub Med Google Scholar Costedoat-Chalumeau N, Galicier L, Aumaître O, et al; Group PLUS. Google Scholar Costedoat-Chalumeau N, Amoura Z, Hulot JS, et al. Pub Med Google Scholar Crossref Costedoat-Chalumeau N, Leroux G, Piette J-C, Amoura Z. A, Interstitial and perivascular brown pigmented granules in the dermis (hematoxylin-eosin-safran staining, original magnification ×100). Skin discoloration plaquenil Sulfasalazine Oral Route Precautions - Mayo Clinic, How Lupus Affects The Skin Lupus Foundation of America How is hydroxychloroquine side effectsHow can plaquenil affect your eyesDoes plaquenil treat scleroderma10-2 visual field test plaquenil need a lens Quinacrine Atabrine is another alternative, but it is prescribed less often because it can sometimes cause a yellow discoloration of the skin. It is sometimes given in addition to hydroxychloroquine if the patient does not respond to Plaquenil alone. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. Plaquenil and skin DailyStrength. Skin Pigmentation with Hydroxychloroquine. She presented 3 months later with multiple skin lesions predominantly on her neck, bilateral forearms, and dorsal feet. The skin lesions were macular or patchy, some well and others poorly demarcated, with a hyperpigmentation of gray to black discoloration, generally annular, but some with irregular morphology. May 21, 2010 The plaquenil made me lose my hair immediately. When it came back in most of it came in white which I read that the medicine can bleach your hair. Then last year I noticed areas on my legs that are brown or maybe it's that my skin has been bleached in areas and is very white. Apr 18, 2009 Re Plaquenil and skin discoloration Reply #11 on April 21, 2009, PM Hyper-pigmentation is a possible side effect of chloroquine medications, chloroquine binds with melanin, causing patchy or mottled spots on areas of skin exposed to sunlight.