Although I cant remember if it was referenced here as a treatment. /gov/pubmed/15617845 "Minocycline, tinidazole and hydroxychloroquine are reportedly capable of destroying both the spirochaetal and cystic L-form of B. It's a very common drug used for those with rheumatoid arthritis people take it for many years. Something is messing with my eyes, no doubt about it. Minocycline treatment started combined with hydroxychloroquine sulfate and the patient discharged with overall improvement." I haven't but it's often prescribed - AKA Plaquenil. It freaks me out because of it's crazy long half -life - 32-50 DAYS (not hours) So, if you want to come off of it...you're waiting a long time for it to clear out of your system. Hydroxychloroquine 200 mg does it have steroids in it Hydroxychloroquine alopecia Chloroquine resistant malaria treatment in children Hydroxychloroquine as third-line agent in type 2 diabetes Then they were randomly divided into three groups. The first group was given the antibiotic doxycycline Doryx for 12 weeks; the second group was given a combination of the antibiotics clarithromycin Biaxin and hydroxychloroquine Plaquenil ; and the third group was given a placebo. Azithromycin and clarithromycin are macrolide antibiotics that have been studied in humans for the treatment of Lyme disease. Both are better tolerated than the older macrolide antibiotic erythromycin in having fewer gastrointestinal side effects. Compare Chloroquine vs Hydroxychloroquine head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Chloroquine rated 10.0/10 vs Hydroxychloroquine rated 6.7/10 in overall patient satisfaction. Ya rhuemeys love it because of it immunosuppressive qualitys ..mess up the eyes ...however some llmd say it inhibits the efflux pump of bugs to make it more succeptable to others abx ..what girlie said ..is 96 hr so a few day n ok but ya a month to clear the system?! Yes its used to reduce inflammation and make other abx's more effective. It can also mess with your eyes so you need to get them checked but I haven't run into anyone that's actually had eye problems from it. Thought that might be the case - hadn't seen it in any of his protocols that I find online. I recommend if you're going on Plaquenil to have a baseline test done. It can also mess with your eyes so you need to get them checked but I haven't run into anyone that's actually had eye problems from it. It's a very common drug used for those with rheumatoid arthritis people take it for many years. I think it tests our Peripheral vision - and you may not notice a change so don't wait for that to happen I failed Visual Contrast Sensitivity as can be expected after mold exposure. Clarithromycin and hydroxychloroquine lyme Antibiotics For Lyme Disease -- How Long Is Enough?, Treatment Options Lyme Disease Plaquenil treatment for vasculitisPlaquenil lymeHow is chloroquine diphosphate used in blood banking Plaquenil hydroxychloroquine "I felt better than I have in 20 years! After 20 years on NSAIDS needed for Lyme arthritis, my kidneys were affected, and when I stopped NSAIDS cold turkey, it was amazing how much pain my body was in. Now a year into Plaquenil I feel like a new person. Get eyes checked every 6 months. Hydroxychloroquine User Reviews for Lyme Disease.. Chloroquine vs Hydroxychloroquine Comparison -. Chronic Lyme Disease Symptoms New Study Teen Vogue. Data from another case series suggested that combined therapy with oral clarithromycin and hydroxychloroquine for at least 3 months may be at least as effective as prolonged doxycycline. Hydroxychloroquine increases the lysosomal pH and is hypothesized to increase macrolide activity. However, few conclusions can be drawn from those clinical studies, as they were retrospective, uncontrolled, observational studies. As macrolides are less active at a low pH, their poor clinical activity might be due to localization of borrelia to an acidic endosome, and their activity improved by alkalinization of that compartment with hydroxychloroquine. MATERIAL/METHODS 235 patients with a multi-symptom complex typical of chronic Lyme disease, ie fatigue, musculoskeletal pain, and neurocognitive dysfunction and with serologic reactivity against B.burgdorferi were treated with a macrolide antibiotic eg clarithromycin. Patients are then randomized ratio 111 to blinded oral follow-up. treatment for 12 weeks with I doxycycline, II clarithromycin combined with hydroxychloroquine, or III placebo. The primary outcome is the physical component summary score PCS of the RAND-36 Health Status Inventory. RAND SF-36 at week 14.