Chloroquine and azithromycin interaction

Discussion in 'Canadian Pharmacies-24h' started by docstud, 25-Feb-2020.

  1. hijack23 Moderator

    Chloroquine and azithromycin interaction


    The importance of this topic is highlighted by a study identifying potential drug–drug interactions with travel-related medications in 45% of travelers using chronic medications, and 3.5% of interactions are potentially serious. Interactions of commonly used travel-related vaccines and medications are discussed here.

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    Jul 07, 2011 Azithromycin and chloroquine do not exhibit any direct pharmacokinetic interactions 115. Chloroquine is known to delay cardiac repolarization through inhibition of the potassium ion channel 116, increasing the chances of prolonging the electrocardiogram QT interval, while azithromycin does not 117. Azithromycin is predicted to increase the exposure to colchicine. Manufacturer advises avoid P-glycoprotein inhibitors or adjust colchicine dose. Severity of interaction Azithromycin and chloroquine are lysosomotropic compounds which show anti-inflammatory activities in various cellular assays. The protein targets for azithromycin are not known 46 and potential protein targets for chloroquine QR2 and ALDH1 have doubtful role in anti-inflammatory activities.

    However, the spacing between the administration of some vaccines that are not given at the same time needs consideration. Concomitant administration of multiple vaccines, including live attenuated vaccines, generally is safe and effective.

    Chloroquine and azithromycin interaction

    Activity of azithromycin or erythromycin in combination with., Azithromycin Interactions BNF content published by NICE

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  5. Safety Announcement. 3-12-2013 The U. S. Food and Drug Administration FDA is warning the public that azithromycin Zithromax or Zmax can cause abnormal changes in the electrical activity of the heart that may lead to a potentially fatal irregular heart rhythm. Patients at particular risk for developing this condition include those.

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    We would like to show you a description here but the site won’t allow us. Jan 05, 2011 Can I Take Benadryl With Azithromycin. The Drug Interaction CheckerThere are factors to be considered in addition to possible interactions between these medications. Learn about drug interactions between azithromycin oral and chlorpromazine oral and use the RxList drug interaction checker to check drug combinations. Drugs A-Z Pill Identifier Supplements Symptom Checker Diseases Dictionary Media

     
  6. alexburzak User

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  7. Phoenikz New Member

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