The differential diagnosis includes actinic keratoses, sebborheic dermatitis, lupus vulgaris, sarcoidosis, drug rash, Bowen’s disease, lichen planus, tertiary syphilis, polymorphous light eruption, lymphocytic infiltration, psoriasis, and systemic lupus erythematosus. Treatment for discoid lupus erythematosus includes smoking cessation and a sunscreen that protects against both UVA and UVB light as well as very strong topical steroids or steroids injected into the lesions. What is plaquenil for lupus Metformin versus hydroxychloroquine for tyle 2 diabetes Symptoms of allergic reaction to plaquenil Hydroxychloroquine sulphate weight gain Discoid Lupus. Lupus is a widespread and chronic lifelong autoimmune disease that, for unknown reasons, causes the immune system to attack the body’s own tissue and organs, including the joints, kidneys, heart, lungs, brain, blood, or skin. Discoid lupus erythematosus DLE is a chronic skin condition of sores with inflammation and scarring favoring the face, ears, and scalp and at times on other body areas. These lesions develop as a red, inflamed patch with a scaling and crusty appearance. The center areas may appear lighter in color with a rim darker than the normal skin. Discoid Lupus Erythematosus of the Eyelids Harvey Siy Uy, MD Introduction Discoid lupus erythematosus DLE is a benign, autoimmune disorder of the skin. While the face, trunk and extremities are frequently affected, eyelid involvement is uncommon and often presents as a diagnostic problem. If a patient does not have any signs of systemic lupus erythematosus, such as generalized hair loss, ulcers in the mouth or nose, Raynaud's phenomenon, arthritis, or fever at the time that he develops discoid lupus, he will most likely only have discoid lupus and will never develop systemic lupus erythematosus. Other oral medications used to treat discoid lupus include retinoids (isotretinoin or acitretin), dapsone, thalidomide (teratogenic, side effects include peripheral neuropathy), azathioprine, methotrexate, or gold. Plaquenil discoid lupus Hydroxychloroquine Plaquenil and Hair Loss Is my Plaquenil., Discoid Lupus Erythematosus - American Osteopathic College of. What will happen if i stop taking plaquenilCheaper alternative to plaquenil Medications commonly used to treat malaria, such as hydroxychloroquine Plaquenil, affect the immune system and can help decrease the risk of lupus flares. Side effects can include stomach upset and, very rarely, damage to the retina of the eye. Lupus - Diagnosis and treatment - Mayo Clinic. Discoid Lupus Erythematosus of the Eyelids. Plaquenil User Reviews for Systemic Lupus. -. Plaquenil is also indicated for the treatment of chronic discoid lupus erythematosus and systemic lupus erythematosus in adults, and for the treatment of acute and chronic rheumatoid arthritis in adults. • Postmarketing cases of life-threatening and fatal cardiomyopathy have been reported with use of Plaquenil and chloroquine. These medications may also prevent lupus from spreading to certain organs, such as the kidney and central nervous system your brain and spinal cord and may help to reduce flares by as much as 50%. Plaquenil and other anti-malarials are the key to controlling lupus long term, and some lupus patients may be on Plaquenil for the rest of their lives. Cutaneous lupus erythematosus CLE is the second most common presenting symptom of autoimmune lupus erythematosus LE. Lesions precede the onset of systemic symptoms in 25 percent of patients, many of whom present to dermatologists for their initial evaluation.1 Prompt diagnosis of CLE requires a thorough understanding of the cutaneous manifestations and clinical spectrum of lupus.