It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Plaquenil pill sjogren's Drug information about chloroquine Puckering of tongue plaquenil Plaquenil and headaches An autoimmune disease; malaria caused by the protozoa Plasmodium malariae; preventive treatment of ovale malaria; disease that causes disc-shaped patches on upper body; preventive treatment of. Plaquenil hydroxychloroquine is considered an older DMARD disease modifying anti-rheumatic drug. Plaquenil was actually first classified as an antimalarial drug, but it is also used to treat certain rheumatic and autoimmune conditions which are unrelated to malaria. Generally, Plaquenil is a treatment option as monotherapy used alone for mild rheumatoid arthritis or as combination. Hydroxychloroquine and is an established, effective, safe and inexpensive therapy, widely used in other autoimmune diseases such as lupus and rheumatoid arthritis. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Hydroxychloroquine for autoimmune diseases Do either hydroxychol/Plaquenil put you at risk for greater., Taking Plaquenil for Rheumatoid Arthritis Chloroquine nursing responsibilities Autoimmune disease such as Sjogrens occurs when the body gets "confused" and attacks healthy tissue instead of just attacking the germs. Basically, the immune system is a bit out of control. Plaquenil works by suppressing the immune system. Do either hydroxychol/Plaquenil put you at risk for.. Hydroxychloroquine in ANCA Vasculitis Evaluation - Full.. Hydroxychloroquine Plaquenil. Anwar Nassar. Munther Khamashta, in Handbook of Systemic Autoimmune Diseases, 2017. 18.4.8 Hydroxychloroquine. Hydroxychloroquine, an antimalarial drug, is traditionally used in the treatment of SLE. Its effectiveness in treating APS has been previously questioned. Hydroxychloroquine and chloroquine are best-known as treatments for malaria, which is caused by a parasite, not a virus. Hydroxychloroquine is also prescribed for autoimmune diseases. But recent. Plaquenil itself probably does not have a direct affect on your immune system - it is a DMARD and is not considered to be an immunosuppressant. However, many with active autoimmune diseases feel that they are not succeptible to many of the common viruses that they are exposed to - somewhat of a silver lining.