There are thousands of quinolones and related drugs, often with different generic names for the same drug, so be aware of the drugs that you are taking and look them up yourself if you have experienced toxicity from these drugs. If you are not familiar with these drugs, please see our Introduction to Fluoroquinolones. Sickle cell disease guidelines hydroxychloroquine Mylan hydroxychloroquine Hydroxychloroquine allergy Plaquenil alcohol side effects By usccessfulu I mean that the Plaquenil did not apparently exacerbate the previous floxing symptoms. However, if a person was still strongly exhibiting symptoms of floxing I, personally, would not take an antimalarial. Chloroquine and hydroxychloroquine both belong to the quinolone family and share similar clinical indications and side effects, including retinal toxicity. Chloroquine-induced retinal toxicity was first described in 1959 and the retinal toxic effects of hydroxychloroquine were later described in 1967 3, 4. Quinolones have been associated with a risk of QT prolongation and TdP. Although extremely rare, TdP has been reported during postmarketing surveillance of norfloxacin. These reports generally involved patients with concurrent medical conditions or concomitant medications that may have been contributory. This list is evolving all of the time as new drugs are being developed. The following is a list of the various chemical names. Is plaquenil a quinolone Hydroxychloroquine Oral Route Before Using - Mayo Clinic, Hydroxychloroquine Plaquenil Toxicity and Recommendations. Hydroxychloroquine 200mg twice a day Other similar medicines such as quinolones and quinine any of the other ingredients of Plaquenil listed in Section 6 below Signs of an allergic reaction include a rash, swallowing or breathing problems, swelling of your lips, face, throat or tongue Plaquenil 200mg Film-coated Tablets - Patient Information Leaflet PIL.. Plaquenil hydroxychloroquine sulfate dose, indications, adverse.. Plaquenil weakness - Road Back Foundation. Aug 02, 2012 I just checked on the web again and plaquenil is a chloroquine, not a quinolone. Rarely it can cause damage to vision by destroying the retina. But I found nothing to make me think it is as dangerous as the quinolones are. Quinolones The first quinolone used was nalidixic acid was marketed in many countries as Negram* followed by many derivatives, such as flumequine Apurone* in France, which are not marketed now. They had an antibacterial effect on Escherichia coli, Proteus, Enterobacter and because of their urinary elimination in high concentrations they were used for treatment of urinary tract infections. Other Name Plaquenil, etc. When taken orally, silver can interact with and reduce the effectiveness of tetracycline, quinolone, and penicillamine. Long term use can cause silver deposition in the skin and mucous membranes leading to an irreversible condition called argyria, characterized by bluish-gray to gray-black pigmentation 7.