Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Chloroquine phosphate fish for sale Plaquenil classification Hydroxychloroquine mechanism of action Hydroxychloroquine is both an antimalarial drug and a disease-modifying anti-rheumatic drug DMARD. As an antimalarial drug, hydroxychloroquine has been shown to accumulate in malaria parasite lysosomes, increasing the pH. Mechanism of action The precise mechanism by which hydroxychloroquine exhibits activity against. Plasmodium. is not known. Hydroxychloroquine, like chloroquine, is a weak base and may exert its effect by concentrating in the acid vesicles of the parasite and by inhibiting polymerization of heme. Rheumatoid Arthritis and Systemic Lupus Erythematosus. Mechanism of action The mechanisms underlying the anti-inflammatory and immunomodulatory effects of Plaquenil are unknown. Indications and Usage for Plaquenil Malaria. Plaquenil is indicated for the treatment of uncomplicated malaria due to P. falciparum, P. malariae, P. ovale, and P. vivax. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Hydroxychloroquine mechanism of action ra Treatments for Rheumatoid Arthritis, PLAQUENIL HYDROXYCHLOROQUINE SULFATE TABLETS, USP DESCRIPTION Hydroxychloroquine for discoid lupus A review of hydroxychloroquine as used by rheumatologists and its side effects. For more information, please visit Hydroxychloroquine for Rheumatoid Arthritis - YouTube. Plaquenil - FDA prescribing information, side effects and uses. Hydroxychloroquine Plaquenil Side Effects & Dosage for.. Hydroxychloroquine HCQ belongs to the group of antimalarial agents, which recognition of its benefit in other diseases except malaria dates back to 1894, when Payne reported that quinine was effective in cutaneous lupus. Since then, therapeutic effects of antimalarial agents were shown in a myriad of other diseases and the evidence for its potential benefit continues to grow. Hydroxychloroquine oral tablet is used for short-term treatment of malaria, but it may be used for long-term treatment of lupus or rheumatoid arthritis. Hydroxychloroquine comes with risks if you. Mechanism of action of hydroxychloroquine as an antirheumatic drug. Fox RI1. Author information 1Department of Rheumatology, Scripps Clinic and Research Foundation, La Jolla, CA 92037. The antimalarial agents chloroquine and hydroxychloroquine have been used widely for the treatment of rheumatoid arthritis and systemic lupus erythematosus.