But you may also be in the grip of a less tangible symptom: chronic fatigue. In fact, fatigue is one of the most common and frustrating RA symptoms.“RA fatigue is a symptom that we rheumatologists really struggle with understanding well," says Yousaf Ali, MBBS, a professor of medicine at the Icahn School of Medicine and chief of the division of rheumatology at Mount Sinai West Hospital in New York City. Chloroquine for malaria prophylaxis Tinnitus and hydroxychloroquine Plaquenil 6 months Fatigue is one of the most common symptoms of lupus. In fact, most people with lupus have fatigue at some point in their illness. “When lupus hit, it was like running into a wall at 80 mph,” says Ann S. Utterback, PhD, a broadcast voice specialist in Virginia who was diagnosed with lupus in 2006. Plaquenil is an antimalarial medication that is also commonly prescribed for a variety of chronic illnesses. I take it to help combat fatigue, and the difference it makes is pleasantly surprising. Exercise and iron infusions have done the brunt of the work, but it’s plain to see that even in the short term, Plaquenil has given me a much-needed boost. Hydroxychloroquine Plaquenil and generics can itself cause fatigue in some users, it can interrupt sleep patterns especially by causing more vivid dreams which in turn makes one more tired. The drug can also lower blood counts red cell, white cells and others too which in turn can cause fatigue. It’s also worth noting that there are other potential causes of fatigue, outside of RA. "It is a systemic type of exhaustion, meaning it affects your whole system instead of just a certain body part."People who have RA often describe their fatigue as a deep tiredness or slowing down, akin to the feeling someone might have while recovering from the flu. Plaquenil and chronic fatigue Fatigue in systemic lupus erythematosus, Things that Changed My Life with Lupus Fatigue, Part 3 Plaquenil arthritis foundationChloroquine phosphate indicationsPlaquenil and dry mouthJohn hopkins research on plaquenil Plaquenil and Fatigue - a study from real-world data. Summary Fatigue is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take medication Enbrel, and have Pain. Will you have Fatigue with Plaquenil - eHealthMe. Is lethargy and tiredness a side effect of hydroxychloroquine?. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. May 23, 2016 Plaquenil hydroxychloroquine is a medication that has been used for many years to help musculoskeletal symptoms and fatigue in patients with autoimmune conditions such as rheumatoid arthritis, lupus and Sjögren’s. Sep 12, 2012 Plaquenil will also help with rashes. It does take awhile to build up in your system before you notice any results Make sure you see an eye doctor for a base line eye exam. If you use plaquenil there is a chance of a serious side effect, retinal damage.is important to get regular eye exams while you are taking this med. Has anyone's doctor suggested Plaquenil for chronic fatigue syndrome? My rheumy has a couple of times. He says it could help with energy level because it is an immune enhancer. My mother took it for rheumatoid arthritis years ago and thinks it's worth a shot. My only concern is the.