Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology. Hydroxychloroquine sulfate中文 Chloroquine is a painless suicide Hydroxychloroquine vs chloroquine Plaquenil nail changes Plaquenil and your eyes. A rare side effect of Plaquenil is damage to the eye's retina. The retina is the light-sensitive tissue at the back of the eye. Using Plaquenil for a long period of time may harm the retina, causing serious vision loss. People with retinal damage from Plaquenil are not aware at first that they are losing vision. Hydroxychloroquine is a well-tolerated medication for various rheumatologic and dermatologic conditions. Its main side effects are gastrointestinal upset, skin rash, headache, and ocular toxicity1. Within the eye, hydroxychloroquine can adversely impact the cornea, ciliary body, and retina1 The AAO published dosing and screening recommendations for chloroquine and hydroxychloroquine in 2016, revising previous recommendations published in 2011. The current maximum daily HCQ dose. While early toxicity may be asymtomatic, patients with more advanced stage of toxicity may complain of color vision changes or paracentral scotomas. Its toxic effects on the retina are seen in the macula. Plaquenil aao 2016 AAO Screening Guidelines for Plaquenil, Hydroxychloroquine toxicity - EyeWiki Hydroxychloroquine and azithromycin Abstract. Background The American Academy of Ophthalmology recommendations on screening for chloroquine CQ and hydroxychloroquine HCQ retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. Pattern of Retinopathy Although the locus of toxic damage is parafoveal in many eyes, Asian. Recommendations on Screening for Chloroquine and.. Despite Plaquenil dosing recommendations, retinal toxicity remains. Plaquenil Uses, Dosage & Side Effects -. The 20 American Academy of Ophthalmology AAO guidelines for screening for hydroxychloroquine retinopathy HR recognized the importance of ideal body weight IBW as opposed to real body weight RBW in determining the safe daily dosing.1, 2 The guidelines state 1 “Obesity is a risk factor because the antimalarials are not retained in fatty tissues. Plaquenil Guidelines Point Out New Risks, New Presentation Written By Jean Shaw, Senior Editor, interviewing Rebekah A. Braslow, MD, Sang Jin Kim, MD, and Michael F. Marmor, MD Add to My To-Do List Based on new data, the authors have revised the Academy’s 2011 guidelines to make screening recommendations more concise and practical. Ophthalmologists play a vital role in educating both patients and prescribing physicians about the risk of toxicity associated with exposure to hydroxychloroquine HCQ and chloroquine CQ drugs.