Additionally, another exception occurred while executing the custom error page for the first exception. Plaquenil is the brand name for the prescription drug hydroxychloroquine. Plaquenil and lung cancer Hydroxychloroquine for vasculities rash Common, nonocular, side effects of chloroquine and hydroxychloroquine include pruritus, headaches, dizziness, and gastrointestinal upset. Less frequent side effects include discoloration of the oral cavity, nails, skin and hair and rash. HCQ myopathy is uncommon and presents with proximal muscle weakness and rarely ventilatory failure. Mg/kg base not to exceed 400 mg 310 mg base PO weekly, starting 2 weeks before exposure and continued for 4 weeks after departure from area With prolonged therapy, obtain CBCs periodically. Melton & Thomas describe the typical safe Plaquenil dosage this way The usual dosage is two 200mg tablets per day. This is generally a "safe" dose for patients having a lean body weight of at least 135 lbs. The generally-regarded safe dosage is 6.5mg/kg/qd, thus the 135 lb. safety threshold. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Plaquenil maculopathy dosage Hydroxychloroquine toxicity - EyeWiki, Plaquenil hydroxychloroquine sulfate dosing, indications. Does plaquenil cause melasmaPlaquenil chronic fatigue syndromePlaquenil and strokeHydroxychloroquine sle mechanism Another study of 4000 patients found a prevalence of 6.8/1000 patients 8. Risk factors that increase the chance of hydroxychloroquine retinopathy include daily dosage, cumulative dose, renal or liver disease, age, and previous retinal disease 9. Hydroxychloroquine Plaquenil Toxicity and Recommendations.. Daily Plaquenil Dosage - Crunching Numbers. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Plaquenil or hydroxychloroquine is under the quinolone family. These medications are initially used in the prophylaxis and treatment of malaria. Plaquenil has replaced chloroquine because it produces less retinal side effects. Side effects. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.