There’s no cure for arthritis, which is unfortunate, but feeling better is definitely possible. The progression of RA may be diminished in severity and duration by the combination of medicines and therapy that work best as determined by you and your physician. Does plaquenil help sjogren& 39 Hydroxychloroquine 200 mg brand name Hydroxychloroquine brand namePlaquenil is a disease-modifying anti-rheumatic drug DMARD approved for adults with RA. It is often given in combination with methotrexate and sulfasalazine a treatment known as triple therapy, to help slow RA disease progression for patients who do not get relief from methotrexate therapy alone. 1,2 The effects of methotrexate and hydroxychloroquine combination therapy vs methotrexate monotherapy in early rheumatoid arthritis patients Lisa Schapink Department of Rheumatology, Sint Maartenskliniek, the Netherlands Hydroxychloroquine Treatment of Rheumatoid Arthritis RICHARD I. RYNES, M. D. Albany, New York A variety of placebo-controlled and open studies have demonstrated the effectiveness of hydroxychloroquine in the treatment of rheumatoid arthritis. Being able to stop joint damage can lessen pain and mean a better quality of life. You can also put off joint damage, and in some cases, you can do more than just slow it down. Treatment rheumatoid arthritis with methotrexate and hydroxychloroquine Rheumatoid Arthritis Treatment Options Johns Hopkins Arthritis Center, Effects of methotrexate and hydroxychloroquine combination therapy vs. Define chloroquinePlaquenil antinflammatory O'Dell JR, Leff R, Paulsen G, et al. Treatment of rheumatoid arthritis with methotrexate and hydroxychloroquine, methotrexate and sulfasalazine, or a combination of the three medications results. Therapies for Active Rheumatoid Arthritis after Methotrexate.. Hydroxychloroquine treatment of rheumatoid arthritis.. Common Questions About Taking Methotrexate for Rheumatoid Arthritis. Originally, hydroxychloroquine was used to prevent and treat malaria and was considered very effective. Now it is generally used for rheumatoid arthritis, but it has also been shown to work well for juvenile arthritis, some lupus symptoms, and other types of autoimmune conditions. Rheumatoid arthritis treatment includes medications that slow the progression of joint damage from rheumatoid. Hydroxychloroquine and. Methotrexate is the most commonly used DMARD. This is. Results from a study published in the New England Journal of Medicine have demonstrated that a combination of conventional DMARDs, an approach called “triple therapy” which includes methotrexate, sulfasalazine, and hydroxychloroquine, can provide significant benefits in patients with RA who have.