It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Chloroquine phosphate where to buy Chloroquine kras Nov 28, 2018 Heavy legs and edema in the ankles occur due to vascular insufficiency. Monitor your diet and eliminate salt when possible. This leads to swelling in the ankles and high-blood pressure. Keeping your legs above your heart helps maintain the flow of venous blood. Heavy legs and edema may be secondary to another illness such as diabetes. Swelling is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take medication Enbrel, and have Osteoporosis. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. Can plaquenil cause edema Please tell me about your swollen ankles/calves.there., Will you have Swelling with Plaquenil - eHealthMe Chloroquine for lupus Plaquenil can cause edema in the feet and legs. One of the warnings says to contact your doctor if you develop swelling/edema in the feet and legs. I had a medication cause me to retain fluid and I gained 6.5 pounds in 2 days. All of it was in my legs and feet. I was miserable. Austin Misha. New Member. Please tell me about your swollen ankles/calves.. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Plaquenil Oral Uses, Side Effects, Interactions.. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Lupus can cause different and varying symptoms in many organs and organ systems, although the skin is the most common. “The hallmark picture of a typical lupus patient is one who comes in with a malar rash a dark reddish, “butterfly” rash or discoid lesions across the face,” he says. Heavy legs and edema in the ankles occur due to vascular insufficiency. Monitor your diet and eliminate salt when possible. This leads to swelling in the ankles and high-blood pressure. Keeping your legs above your heart helps maintain the flow of venous blood. Heavy legs and edema may be secondary to another illness such as diabetes.