One class of medications can lead to more severe vision loss in people with the wet form of the disease, and another class of drugs may have a beneficial effect. Fortunately, very few prescription drugs have any known detrimental effects for people with AMD. Chloroquine concentration lysosome What manufacturer does walmart pharmacy use for hydroxychloroquine As the disease advances, drusen can grow in number and become larger.” Causes There’s no known cause, but the biggest risk factors include age AMD is most likely to occur after age 60, race whites are more likely to get AMD than African Americans or Hispanics and family history. The risk for retinal toxicity begins once the patient has used Plaquenil for five to seven years and/or has taken a cumulative dose of more than 1,000g. Patients with renal or hepatic dysfunction are at an increased risk of toxicity. 1 Other risk factors for retinal toxicity include short stature, obesity. RARE side effects. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Doctors often put patients with certain potentially life-threatening cardiovascular conditions on this blood thinner. Warfarin (Coumadin®), which is an anticoagulant blood thinner, is one exception. Can plaquenil cause drusen Macular degeneration and lupus" Lupus Community - Support Group, Pause the Plaquenil? Plaquenil and cancer riskHyperprolactinemia caused by chloroquinePrednisone for plaquenilHydroxy chloroquine 400 mg In some people, Plaquenil can cause a condition called hydroxychloroquine retinopathy, often referred to as bulls-eye maculopathy. The condition sometimes resembles a target, or bulls-eye ring, on the retina surrounding the macula. Plaquenil Side Effects on Your Eyes and Vision. Common and Rare Side Effects for Plaquenil Oral. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. Feb 19, 2020 Tell your doctor if you experience serious side effects of Plaquenil including. muscle weakness, twitching, uncontrolled movement, loss of balance or coordination, blurred vision, light sensitivity, seeing halos around lights, Anyway I was diagnosed with dry macular degeneration 7 years ago. A recent exam showed it has worsened. I have also seen 3 rheumatologists, and 2 of them say I should take Plaquenil and the risk of damage to my macula is not big enough to not take the Plaquenil. One doctor says I should NOT take it. May 16, 2011 Hydroxychloroquine Plaquenil; HCQ has been an important and effective drug for the treatment of lupus erythematosus and related autoimmune and inflammatory diseases for half a century, although its potential to cause retinal damage continues to raise concern among rheumatologists.