Am very deflated as feel have come to stand still in my progression in fact have gone back somewhat (probably have done too much over the festive!! Am trying to be positive and keep telling myself I WILL get back to near as normal as possible. Can anyone assure me that YES the Lupus drug will kick in and I will be able to control my life again. Bpi nite burn and hydroxychloroquine Hydroxychloroquine plaquenil drug class Can i take a multivitamin with plaquenil Hydroxychloroquine does take a while to take effect. Arthritis UK gives a figure of around 12 weeks, whilst the American College of Rheumatology says, "symptoms can start to improve after 1-2 months, but it may take up to 6 months before the full benefits are felt". My own rheumy said, "3-4 months". Hearing problems, such as ringing or ticking in the ears, or hearing changes Plaquenil may have toxic effects on your inner ear Loss of balance, coordination, room spinning, or other vertigo. Plaquenil’s long half-life in the body can cause irreversible and progressive damage, Dr. Fung said. Similarly, one study reported that 16 women who’d taken hydroxychloroquine or chloroquine, or a combination of the agents, showed no improvement seven years after stopping drug therapy, and progression occurred in six of the cases. 2 Wishing you all a good New Year and a Healthy one Kelpie21Took me a couple of weeks... I want to get back to work, exercise and enjoying normal day to day things such as being able to chopping onions, going for a drive and shopping!!!!! Does plaquenil have life long effects Hydroxychloroquine Oral Route Side Effects - Mayo Clinic, Plaquenil Hydroxychloroquine - Side Effects, Dosage. What are the side affects of hydroxychloroquinePlaquenil cardiacDigoxin chloroquineManagement of plaquenil maculopathyChloroquine autophagic flux Hello all, I am currently new to this site and ran across the discussion about stopping Plaquenil. I have been taking Plaquenil for about 8-9 months and thought that it was not helping me because I still have a fair amount of joint pain, fatigue, muscle pain and so many other issues. Stopping plaquenil. DailyStrength. Rx Side Effects New Plaquenil Guidelines and More.. Hydroxychloroquine Side Effects, Dosage, Uses, and More. That's a real common side effect of Lupus is unexplained rashes. If you've ever had an allergic reaction to a drug then this is the type of reaction you'd have if you were allergic to the Plaquenil; and they'd stay until the Plaquenil was out of your system. If they're coming and going more than likely it isn't the Plaquenil. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur.