Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Side effects of plaquenil and methotrexate Malaria prophylaxis with chloroquine Plaquenil toxicity symptoms Plaquenil and your eyes. A rare side effect of Plaquenil is damage to the eye's retina. The retina is the light-sensitive tissue at the back of the eye. Using Plaquenil for a long period of time may harm the retina, causing serious vision loss. People with retinal damage from Plaquenil are not aware at first that they are losing vision. WARNING/CAUTION Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect For all uses of Plaquenil hydroxychloroquine PLAQUENIL is indicated for the treatment of acute attacks and suppression of malaria. Warning In recent years, it has been found that certain strains of P. falciparum have become resistant to 4-aminoquinoline compounds including hydroxychloroquine as shown by the fact Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Plaquenil warnings vision Hydroxychloroquine Side Effects, Dosage, Uses, and More, Plaquenil Indications, Side Effects, Warnings - Hydroxychloroquine sulfate weight gainPlaquenil pulmonary hypertensionChloroquine quinineFolic acid and hydroxychloroquine If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. Plaquenil Side Effects on Your Eyes and Vision. PLAQUENIL®. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Find user ratings and reviews for Plaquenil oral on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfaction. that I had issues with my vision. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking hydroxychloroquine and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Call your doctor at once if you have Plaquenil tablets contain the active ingredient hydroxychloroquine, which is a type of medicine called a disease-modifying anti-rheumatic drug DMARD. It is used to treat rheumatoid arthritis.