My rheumie says that although it has been proven safe, once he finds out that I'm pregnant he's going to take me off of it. Corticosteroids (such as prednisone) are generally considered safe for use during pregnancy because they do not reach the fetus in an active form.2 Cytotoxic medications such as methotrexate are stopped during pregnancy. Also one thing you have to remember is Plaquenil takes so long to enter your body to help symptoms that it will pry take just as long to leave your system so either way your body is still going to have it in it's system why go off of it throw your body off course then try to take it again, it's like starting from fresh to get your symptoms under control. Andrea I just copied this from ***** Immunosuppressant medications, which may be prescribed for severe lupus, can cause birth defects. Does plaquenil help with sex drive Plaquenil and arava Chloroquine and anxiety Side effects of plaquenil medication Objective. To investigate the effect of hydroxychloroquine HCQ in pregnant women with systemic lupus erythematosus SLE. Methods. In SLE pregnancies of a single Dutch center 2000–2015, lupus activity and flares before and during pregnancy and postpartum were assessed using the SLE Disease Activity Index SLEDAI/SLEPDAI SLEDAI adjusted for pregnancy. Find patient medical information for Hydroxychloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Preterm birth in lupus is usually not due to antiphospholipid antibodies, but due to pre-eclampsia and premature rupture of membranes. Risk factors for preterm birth in general include active lupus, high dose prednisone, and renal disease. Maternal hypertension in the second trimester is a good predictor. I have never taken plaquenil as I have a seizure disorder as well, however, I do know that my Rheumy told me that the only safe drug to take during pregnancy is prednisone. Most certainly I wouldn't be on it if I were to have a child. Thankfully some have had successful births on prednisone but that is a strong medication just like pain medication it can harm a baby.. Hydroxychloroquine and prednisone in pregnancy Hydroxychloroquine HCQ in lupus pregnancy double-blind., Hydroxychloroquine Oral Uses, Side Effects, Interactions. How long is plaquenil goodHydroxychloroquine discontinueSynthesis of chloroquine phosphate ppt What is Prednisone? Prednisone has active ingredients of prednisone. It is often used in rheumatoid arthritis. Check the latest outcomes from 345,583 Prednisone users, or browse all drugs. What is Hydroxychloroquine sulfate? Hydroxychloroquine sulfate has active ingredients of hydroxychloroquine sulfate. It is often used in rheumatoid arthritis. Prednisone and Hydroxychloroquine sulfate drug.. Lupus and Pregnancy Johns Hopkins Lupus Center. Obstetric Nephrology Lupus and Lupus Nephritis in Pregnancy. Hydroxychloroquine HCQ is often needed to manage disease activity in systemic lupus erythematosus SLE during pregnancy. The purpose of this study was to examine lupus activity and pregnancy outcomes in women with SLE treated or not treated with HCQ during pregnancy. Hydroxychloroquine Use in Lupus Patients during Pregnancy Is Associated with Longer Pregnancy Duration in Preterm Births. 1Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands. 2Department of Gynecology and Obstetrics, University Medical Center Utrecht, Utrecht, Netherlands. We conducted a randomized, controlled study to assess the need for hydroxychloroquine HCQ during lupus pregnancy and to assess safety. Twenty consecutive pregnant patients with similar characteristics were enrolled. The HCQ group included eight patients with systemic lupus erythematosus SLE and two with discoid lupus erythematosus DLE.