It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Dose of hydroxychloroquine Will plaquenil treat lupus and rheumatoid arthritis Preparation & Administration. Hydroxychloroquine comes in 200 mg tablets and is taken orally. The dose provided will be based upon a calculation of 6.5 mg/kg subject’s weight, which is the dose range commonly used to treat rheumatoid arthritis and lupus. Dosages will be rounded to the nearest 100 mg. Hydroxychloroquine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies, or to become more depressed. If you or your caregiver notice any of these side effects, tell your doctor right away. This medicine may cause hypoglycemia low blood sugar. An increased incidence of cutaneous reactions to hydroxychloroquine has been postulated to occur in patients with dermatomyositis. Objective To determine if adverse cutaneous eruptions due to hydroxychloroquine are more common in patients with dermatomyositis than in those with cutaneous lupus erythematosus. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Hydroxychloroquine related rash on external genitali Successful Treatment of Hydroxychloroquine-Induced., Hydroxychloroquine Oral Route Precautions - Mayo Clinic Aralen malaria medicationQuit plaquenilHow long for plaquenil to workWhat to expect when taking plaquenil Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Hydroxychloroquine-Induced Retinal Toxicity - American.. Adverse Cutaneous Reactions to Hydroxychloroquine Are More.. Rashes, Skin Care and Cutaneous Lupus What You Should Know. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Was put on steroids 4 days after onset. Been on them 4 days is not getting any better. Miserable is all I can say othervthan itching terrible. ” Druginformer Identified Side Effects Flatulence, Dizziness, Nausea, Pruritus, Alopecia, Purpura, Diarrhoea, Hallucination. Genital herpes. Herpes is a viral infection caused by the Herpes simplex virus which is often referred to as HSV. There are two types of herpes viruses that can affect either skin or mucous membranes. The other one is HSV-1, which most often adheres to the mouth or lips, and the other is HSV-2, which usually adheres to the genital area.