Yesterday my rheumatologist started me on hydroxychloroquine as well. Is anyone else on this combination and have you had any problems with it as I know hydroxychloroquine can cause eye sight problems. Malarone for chloroquine resistance ncbi Plaquenil for limited scleroderma Benefits of taking plaquenil I have been diagnosed with Limited Scleroderma. My choices are Methotrexate, Plaquenil or Sulfasalzine Azulfidine. I researched them and determined Plaquenil would be my last choice, although it was his first, because I already have lattice degeneration of the retina in both eyes and one of the potential side effects is retinal problems. I am on both methotrexate and plaquenil. I have been on plaquenil for over a year and a half and methotrexate since September. I have had no side effects from either one. I get my eyes checked every six months and I am now at once a month on blood work for my liver enzymes used to be every 2 weeks. Compare Methotrexate vs Plaquenil head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Methotrexate rated 6.7/10 vs Plaquenil rated 6.8/10 in overall patient satisfaction. Recently my eyes have felt sore and, after posting a question on this site, I am seeing my GP on Monday. Thanks Hi Catjones I have been taking this combination, started on both of them in January this year. Methotrexate or plaquenil Rheumatoid Arthritis Treatment Options Johns Hopkins., Which would you pick and why? - Plaquenil or Methotrexate Plaquenil and optic neuropathyStop antibodies drug plaquenilHydroxychloroquine and glaucomaWoman in grey hydroxychloroquine-induced hyperpigmentation Mar 21, 2014 Ok, here is a question that we all could probably use an answer to; Methotrexate or Plaquenil for CREST Scleroderma. I have read Plaquenil is better for Lupus but Methotrexate is better for Scleroderma. Doctor said either is fine, but she wants me to choose. What is your experience with either or both. I need reviews. Methotrexate or Plaquenil - Scleroderma - Inspire. Methotrexate vs Plaquenil Comparison -. Methotrexate and plaquenil -. Jul 18, 2014 Cardiovascular risk evaluation. Prior to elective surgery, the risk of perioperative cardiovascular events must be assessed. Overall, individuals with rheumatoid arthritis have a higher risk of myocardial infarction which is similar to individuals with diabetes mellitus or a person 10 years older than the age of the patient. Original Article from The New England Journal of Medicine — Treatment of Rheumatoid Arthritis with Methotrexate Alone, Sulfasalazine and Hydroxychloroquine, or a Combination of All Three Medications Methotrexate vs plaquenil side effects long term and short term The only problem is the Plaquenil causes severe headaches that interfer with my daily activities also. But the Dr suggested I try Methotrexate instead.