One class of medications can lead to more severe vision loss in people with the wet form of the disease, and another class of drugs may have a beneficial effect. Fortunately, very few prescription drugs have any known detrimental effects for people with AMD. Hydroxychloroquine tramadol interaction Chloroquine phosphate where to buy Visual fields in chloroquine My Mom took Plaquenil for many years for her rheumatoid arthritis. She was seeing an opthamologist every six months during that entire time. After many years, her opthamologist recommended she stop immediatley which she did but unfortunatley has one eye with macular degeneration which he says is due to her plaquenil intake. Aug 16, 2012 Anyway I was diagnosed with dry macular degeneration 7 years ago. A recent exam showed it has worsened. I have also seen 3 rheumatologists, and 2 of them say I should take Plaquenil and the risk of damage to my macula is not big enough to not take the Plaquenil. One doctor says I should NOT take it. The investigators think that there is a connection between the use of plaquenil and the prevention of Age related macular degeneration AMD. The investigators believe that the use of plaquenil makes bruch's membrane thicker, thereby preventing Chroidal Neovascularization CNV growth. Doctors often put patients with certain potentially life-threatening cardiovascular conditions on this blood thinner. Warfarin (Coumadin®), which is an anticoagulant blood thinner, is one exception. Does plaquenil cause macular degeneration Pause the Plaquenil?, What about Plaquenil and Macular Degeneration? - Inspire Chloroquine prevention dosePlaquenil for worms The incidence of Plaquenil related macular problems increases when approaching a dose of 600 to 700 mg. per day. The average dose is 400 mg. per day. This is a very safe dose. Retina related complications have been reported at this dosage level too. Conditions Plaquenil-related Eye Problems Eugene Eye Care. Plaqenil Role in Prevention of Age Related Macular Degeneration. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Plaquenil-induced maculopathy is a form of retinal toxicity that is associated with long-term use of of the anti-inflammatory medication plaquenil. The drug-induced maculopathy is associated with the following risk factors Cumulative dose level of 1,000 grams of plaquenil; Patients with existing retinal or macular disease; Patients over the. While Plaquenil can cause toxicity damage to the macula, it will not cause a macular pucker. If you are on Plaquenil, it is recommended that you have your retina checked regularly by an ophthalmologist, including imaging studies, which can help find damage to the macula. Patients often ask if their medications affect the risk of vision loss from age-related macular degeneration AMD. One class of medications can lead to more severe vision loss in people with the wet form of the disease, and another class of drugs may have a beneficial effect.