In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Side effects of chloroquine ncbi Chloroquine storage temp Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. While a high daily dose is a risk factor for retinotoxicity, the risk also increases as an individual’s cumulative lifetime dosage increases. The risk of a toxicity sharply increases after 5 years, with majority of cases of retinotoxicity occurring in patients that have had a cumulative dose exceeding 1000g of hydroxychloriquine Plaquenil. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. Is plaquenil dangerous Dangers of plaquenil - Answers on HealthTap, Plaquenil Risk Calculators Side effects from stopping plaquenilMacular thinning and plaquenilChloroquine diphosphate 25 μmHydroxychloroquine toxicity octDo you have to take methotrexate and plaquenil together Although they are uncommon, Plaquenil has side effects that may affect your eyes. Plaquenil and Your Eyes In some people, Plaquenil can cause a condition called hydroxychloroquine retinopathy, often referred to as bulls-eye maculopathy. Plaquenil Side Effects on Your Eyes and Vision. Plaquenil Side Effects Common, Severe, Long Term -. Plaquenil Uses, Dosage & Side Effects -. So I ran out of my plaquenil and the Rheum. that prescribed it I am no longer seeing and wont re-fill it and I dont see my new Rheum. until Decemeber 23rd. I am nervous to see what will happen. The pharmacist said there wont be any danger just stopping it. Im just nervous to see what my body will do. Has anyone gone off the plaquenil and what happened? I hear my new Rheum. is all for it so I. Plaquenil can be dangerous to children, who are particularly sensitive to the drug. Kids shouldn't take Plaquenil as a long-term treatment. Overdose can be fatal in children. Today, Plaquenil and other antimalarials are also used to treat and help prevent symptoms caused by certain autoimmune diseases such as rheumatoid arthritis RA, systemic lupus erythematosus, and discoid lupus, even though these diseases are not caused by malaria parasites.