Most importantly, you help support continued development of this site. The majority of cases of retinotoxicity have occurred in patients that have had a cumulative dose exceeding 1000g of hydroxychloriquine (Plaquenil). This level is reached in about 7 years with the most common daily dose of Plaquenil, 400 mg/day (200 bid). Hydroxychloroquine 200 mg daily Class drug plaquenil The risk of HPV infection can also be reduced by vaccination. Cervarix and Gardasil are two vaccines that have been shown to reduce the risk of HPV infection. However, they are most effective when they are given before young people become sexually active. We compared the risk of high-grade cervical dysplasia and cervical cancer among women with systemic lupus erythematosus who started immunosuppressive drugs versus hydroxychloroquine. Methods We identified systemic lupus erythematosus patients initiating immunosuppressive drugs or hydroxychloroquine using claims data from two US commercial health plans and Medicaid 2000–2012. High-risk HPVs cause about 5% of all cancers worldwide, with an estimated 570,000 women and an estimated 60,000 men getting an HPV-related cancer each year. Cervical cancer is among the most common cancers and a leading cause of cancer-related deaths in low- and middle-income countries, where screening tests and treatment of early cervical cell changes are not readily available. It now solely uses real body weight (rather than ideal body weight) based on new recommendations from a 2014 study (1). Disclaimer: This tool is designed to help eye care professionals better understand the risk the of retinotoxicity from hydroxychloroquine. Please note: This calculator was modified in 9/2015. Plaquenil cervical cancer risk Cervical Cancer Risk Factors -, Risk of high-grade cervical dysplasia and cervical cancer in. Hydroxychloroquine with or without foodPlaquenil pediatric dose for sle This is why the HPV vaccine works best when given before any exposure to HPV. You should get screened for cervical cancer regularly, even if you received an HPV vaccine. More Steps to Help Prevent Cervical Cancer. These things may also help lower your risk for cervical cancer— Don’t smoke. Use condoms during sex.* Limit your number of sexual partners. What Can I Do to Reduce My Risk of Cervical Cancer? CDC. HPV and Cancer - National Cancer Institute. Cervical dysplasia Is it cancer? - Mayo Clinic. Compare Methotrexate vs Plaquenil head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Methotrexate rated 6.7/10 vs Plaquenil rated 6.8/10 in overall patient satisfaction. Persistent human papillomavirus HPV infection is already a known major risk factor for cervical cancer, one that is affected by a number of variables, including older age, the HPV genotype, any coexisting infections, inflammation, and immunosuppression. Table 3 shows the relationship between the use of the drugs hydroxychloroquine, prednisolone, azathioprine and methotrexate and the development of cancer. The cells show the numbers and percentages of patients who developed a lymphoma or any cancer amongst patients taking a particular drug vs those not taking it.