Antibiotics containing chemicals called sulfonamides can trigger a reaction if you have a sulfa allergy. These antibiotics include combination drugs: An allergy to sulfonamide medications is different from having an adverse reaction to wine or food that contains sulfites. Sulfasalazine and hydroxychloroquine rheumatoid arthritis Hydroxychloroquine related rash on external genitalia Dress hydroxychloroquine Plaquenil and dental implants A sulfonamide is a useful alternative to a tetracycline or an erythromycin in the treatment of trachoma and inclusion conjunctivitis. A sulfonamide with pyrimethamine is useful in the treatment, and suppression, of malaria due to chloroquine-resistant strains of Plasmodium falciparum. Free heme is generated by the parasite while digesting the host cell’s parasite polymerizes the heme to hemozoin to avoid the toxic effects of the free heme; however, chloroquine accumulates in the food vacuoles of plasmodia and prevents polymerization of heme. Consequently, free heme causes the lysis of the parasite along with the red blood cells. Sulfasalazine SSZ, sold under the trade name Azulfidine among others, is a medication used to treat rheumatoid arthritis, ulcerative colitis, and Crohn's disease. It is considered by some to be a first line treatment in rheumatoid arthritis. If you have HIV/AIDS, you may have an increased sensitivity to sulfonamide medications. Having a reaction to sulfites in something you eat or drink doesn't mean you'll be allergic to sulfonamide medication. Is chloroquine sulfonamides Plaquenil and Sulfa Allergies" Lupus Community - Support Group, Antimalarial Drugs – Quinine, Quinidine, Sulfonamides & more Chloroquine for treating malaria Sulfonamides and other drugs that inhibit folic acid synthesis have a high therapeutic index because A. humans do not use folic acid. B. humans do not synthesize folic acid but obtain it in their diets. C. humans synthesize folic acid by a process that is not sensitive to sulfonamides. D. none of these Micro Chapter 9 Flashcards Quizlet. Sulfasalazine - Wikipedia. Can you take Hydroxychloroquine if you are allergic to sulfa drugs?. An allergy to sulfonamide medications is different from having an adverse reaction to wine or food that contains sulfites. Having a reaction to sulfites in something you eat or drink doesn't mean you'll be allergic to sulfonamide medication. If you have HIV/AIDS, you may have an increased sensitivity to sulfonamide medications. Chloroquine 25 mg/kg over 3 days with a single dose of SP as described above. SP plus amodiaquine This combination has been shown to produce a faster rate of clinical recovery than SP and chloroquine, but is clearly inferior to artemisinin-based combinations ACTs for the treatment of malaria. Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication.