Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Plaquenil generic pictures Oct testing in plaquenil macular toxicity Plaquenil for lichen planopilaris Chloroquine and hydroxychloroquine belong to the quinolone family. They are related drugs with similar clinical indications for use and similar manifestations of retinal toxicity, although their therapeutic and toxic doses differ. Hydroxychloroquine is metabolized and secreted by both the liver and the kidneys. Therefore, disturbed renal or hepatic function might reduce HCQ clearance and increase the propensity for toxicity. Older age may also be associated with increased risk of macular toxicity, possibly due to the pre-existence of age-related macular changes that might not allow for the identification of early signs of toxicity. Hydroxychloroquine sulfate HCQ, Plaquenil is an analogue of chloroquine CQ, an antimalarial agent, used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune disorders. Its use has been associated with severe retinal toxicity, requiring a discontinuation of therapy. Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Macular society hydroxychloroquine Hydroxychloroquine-Induced Retinal Toxicity - American., Retinal Physician - Hydroxychloroquine Maculopathy An. What is hydroxychloroquine used for arthritisHow long is it safe to take hydroxychloroquinePlaquenil and doxycycline The Macular Society supports those with Macular Degeneration, their families and their carers; offering counselling and other services, as well as funding crucial research into the disease. Macular Society. Retinal toxicity associated with chronic exposure to.. Recommendations on Screening for Chloroquine and.. Hydroxychloroquine is a medicine that is effective in treating various long-term inflammatory disorders of the joints and skin. In general, it is a safe and cost-effective medication, particularly when compared to newer anti-inflammatory medicines which can more significant adverse effects on the body. Hydroxychloroquine is a medication used to treat several conditions, including active rheumatoid arthritis, juvenile idiopathic arthritis, discoid and systemic and cutaneous lupus erythematosus, solar urticarial. HCQ is widely used for the treatment of rheumatic diseases, particularly lupus and RA. It is generally well tolerated, but retinopathy is a concern. Retinopathy is rare, but is sight threatening, generally irreversible and may progress even after cessation of therapy.