It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. Can you drink on plaquenil Chloroquine peremption How does plaquenil affect vision Plaquenil mastocytosis And quantified using ERG. Which type of ERG to apply depends on the mechanism and site of retinal toxic-ity. Identifying retinal toxicity due to chloroquine or hydroxychloroquine is a pertinent application of mfERG. SIGNS OF TOXICITY Plaquenil toxicity first affects small areas of the retina between 5° and 15° from the fovea. Figures 2 and 3 show In the rest one 2 eyes the RRD were normal. Six months after interruption of HC the mfERG and the EOG improved in 2 cases. These results postulate that the mfERG may be used as an alternative method, perhaps more sensitive, for the detection of the HC retinopathy and the follow up of the patients on hydroxychloroquine. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Hydroxychloroquine comes as a tablet to take by mouth. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Hydroxychloroquine erg Detection of Early Hydroxychloroquine Retinal Toxicity., Assessing hydroxychloroquine toxicity by the multifocal ERG. Hydroxychloroquine and trametinibHydroxychloroquine sulfate 200 mg tab sPlaquenil for lupus nephritisPlaquenil ehlers danlos The American Academy of Ophthalmology released an updated set of screening recommendations for hydroxychloroquine Plaquenil and chloroquine to account for the many studies that have shown the effects of these medications on the retina 1. It succinctly makes the case for screening, and Hydroxychloroquine And Chloroquine Screening 2016 AAO.. Hydroxychloroquine-Induced Retinal Toxicity - American.. Hydroxychloroquine Plaquenil Toxicity and Recommendations.. Compared with focal ERG, mfERG is more appropriate for the evaluation of chloroquine and/or hydroxychloroquine toxicity because it generates local ERG responses topographically across the posterior pole and can document a parafoveal or extramacular depression in early retinopathy or bull's eye distribution of ERG depression in late stages. Compared with focal ERG, mfERG is more appropriate for the evaluation of chloroquine and/or hydroxychloroquine toxicity because it generates local ERG responses topographically across the posterior. Multifocal ERG has the ability to detect early macular dysfunction, so it should be included as part of baseline screening. A maximum daily dose of Plaquenil of 5.0mg/kg real weight is recommended. Communication with the prescribing physician is also key to proper treatment and management of your patient.