Antibiotics containing chemicals called sulfonamides can trigger a reaction if you have a sulfa allergy. These antibiotics include combination drugs: An allergy to sulfonamide medications is different from having an adverse reaction to wine or food that contains sulfites. Chloroquine against malaria Shortness of breath related to plaquenil Chloroquine proguanil antimalarial Adults. 200 mg 155 mg base to 400 mg 310 mg base PO per day, administered as a single dose or in 2 divided doses. Antimalarials and/or glucocorticoids are of benefit and may be used for the treatment of SLE without major organ manifestations; however, judicious use of hydroxychloroquine is recommended. To make sure hydroxychloroquine is safe for you, tell your doctor if you have a history of vision changes or damage to your retina caused by an anti-malaria medication; heart disease, heart rhythm disorder such as long QT syndrome; diabetes; a stomach disorder; an allergy to quinine; liver or kidney disease; Plaquenil isn't a 'sulfa' drug which means a certain sort of antibiotic, the sulfonamides. Plenty of people who are allergic to those sulfa drugs take Plaquenil without any problem. This sounds all very odd to me! If you have HIV/AIDS, you may have an increased sensitivity to sulfonamide medications. Having a reaction to sulfites in something you eat or drink doesn't mean you'll be allergic to sulfonamide medication. Plaquenil sulfate allergy Plaquenil, Plaquenil Sulfate, Quineprox hydroxychloroquine., Plaquenil, Plaquenil Sulfate, Quineprox. Can plaquenil cause eyes to burn or waterChloroquine malaria prophylaxisChloroquine phosphate injection spc You can take Advil or another NSAID while taking Plaquenil hydroxychloroquine as long as NSAID isn't contraindicated for you. Asked in Allergies, Medication and Drugs, Antihistamines allergy. Can you take hydroxychloroquine with antihistamine - Answers. Plaquenil when allergic to sulfa? Lupus Forums at The Lupus.. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. I had been taking plaquenil since April for my lupus and sjogrens. It was working really well and just recently my rheumy told that I was in remission. I felt great. Then I had an allergic reaction to the plaquenil - a rash all over my body, neck, arms and legs. I stopped taking it 1 week ago. Hydroxychloroquine Sulfate Allergy Definition This is a medication that is classified as an antimalarial drug. However, it has a number of other uses including lupus, arthritis, and various other autoimmune disorders. As with other drugs, an allergic reaction may be manifested by rash, headaches, blurred vision, or GI upset.