Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Does plaquenil cause dry eyes Chloroquine injection intravenous Seroqul and chloroquin Rosuvastatin and hydroxychloroquine NSAIDs are usually allowed during the first trimester only, because of potential adverse effects on the fetal ductus arteriosus. Plaquenil hydroxychloroquine has a good safety record in lupus pregnancy, and is usually continued if needed to control maternal lupus. Management and Monitoring Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. Rarely, hydroxychloroquine can lead to anemia in some individuals. As PLAQUENIL may enhance the effects of a hypoglycemic treatment, a decrease in doses of insulin or antidiabetic drugs may be required. Drugs That Prolong QT Interval And Other Arrhythmogenic Drugs. PLAQUENIL prolongs the QT interval and should not be administered with other drugs that have the potential to induce cardiac arrhythmias. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Effects of plaquenil in pregnancy Plaquenil Oral Uses, Side Effects, Interactions, Pictures., Hydroxychloroquine Plaquenil Chloroquine antibody Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells. Rare but potentially serious eye toxicity can occur. Hydroxychloroquine Plaquenil Side Effects & Dosage for.. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. OR of congenital defects and live births. Other studies have reported that HCQ is safe to use during pregnancy but had no control group 35–40. All 4 of the studies 27–30 assessed the presence of congenital defects in babies born to women with autoimmune diseases Additional file 1, Table S2 and Figure 2a. Plaquenil = Hydroxychloroquine. ›. Antimalarial drugs in the treatment of rheumatic disease View in Chinese ago. Three of these drugs are now primarily used due to their safety profile. Chloroquine and hydroxychloroquine HCQ are 4-aminoquinoline derivatives. Plaquenil is generally well-tolerated, but side effects are possible. Common side effects linked to Plaquenil include nausea and diarrhea. Taking the medication with food eases nausea for most people taking the drug. Less common side effects include skin rashes, hair thinning, and weakness.