Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Has there been a plaquenil class action lawsuit Hydroxychloroquine and naproxen Plaquenil drug action Plaquenil treatment 1cd 10 I also have pigmentation on areas of my body - maily my arms/elbows. It also gets better or worse depending on how high of a dose I am of Plaq. The lower the dose 200mg the lighter the pigmentation is, the higher the dose 400mg/day the darker and larger the spots get. weird. Rheumy said to not worry about it. It doesn't hurt, itch etc. Hello all, I am currently new to this site and ran across the discussion about stopping Plaquenil. I have been taking Plaquenil for about 8-9 months and thought that it was not helping me because I still have a fair amount of joint pain, fatigue, muscle pain and so many other issues. Hyperpigmentation occurs when a person develops darker patches on the skin, such as age spots or melasma. Learn about the causes, types, and treatments for hyperpigmentation here. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil and hyperpigmentation Skin Discoloration and Plaquenil - Arthritis Information, Stopping plaquenil. DailyStrength Hydroxychloroquine for lichen planus eye side effectsChloroquine retinal cellDoes plaquenil change phLichen planopilaris plaquenilMorrowind alynu aralen Hydroxychloroquine Plaquenil® is a 4-amino-quinoline antimalarial medication that is widely used to treat systemic lupus erythematosus SLE, rheumatoid arthritis, and related inflammatory and dermatological conditions. It is a hydroxylated version of chloroquine, with a similar mechanism of action. However, following an identical dose of. Hydroxychloroquine DermNet NZ. Hyperpigmentation Treatment, types, and causes. Hydroxychloroquine Side Effects Common, Severe, Long Term.. Hydroxychloroquine Plaquenil and chloroquine cause ocular toxicity to various parts of the eye such as the cornea, ciliary body, and retina. Chloroquine can also induce cataract formation; however, no reports of hydroxychloroquine and cataract have been reported. This article focuses upon hydroxychloroquine retinopathy. Disease We report two cases of hydroxychloroquine-induced hyperpigmentation presenting in a 50-year-old Caucasian female case 1 and a 78-year-old female case 2, both receiving 400 mg per day. Case 1 had an arthritis predominant undifferentiated connective tissue disease, which was treated with hydroxychloroquine for 4-5 years. I think it's due to Hydroxycholoroquine-induced hyperpigmentation an example of drug-induced skin pigmentation. I thought it worth showing those of you on the medication. Why is it so much worse on the right forearm? Well she's only just started to drive again.