In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. John hopkins research on plaquenil Rash from hydroxychloroquine Your eye care provider can examine the macula and detect subtle changes before you begin to notice any symptoms of problems. As a result, all patients taking plaquenil should have an examination approximately every six months. The macula should be examined through a dilated pupil. The incidence of Plaquenil related macular problems increases when approaching a dose of 600 to 700 mg. per day. Plaquenil, hydroxychloroquine HCQ, is an anti-malarial medication that has been proven to be useful in the treatment of patients with rheumatoid arthritis RA, systemic lupus erythematosus SLE and other inflammatory and autoimmune diseases. Hydroxychloroquine is a well tolerated medication for various rheumatologic and dermatologic conditions. Its main side effects are gastrointestinal upset, skin rash, headache, and ocular toxicity. Within the eye, hydroxychloroquine negatively impacts the cornea, ciliary body, and retina. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. Eye problems on hydroxychloroquine Hydroxychloroquine-Induced Retinal Toxicity - American., The Risk of Retinal Toxicity with Plaquenil Can plaquenil cause anemiaPlaquenil blurry vision reviews I have only been taking Hydroxychloroquine for just over a year and have had no problems. I told the rheumatologist that I had early stages macular degeneration but they said it was not a problem. Recently i have had eye problems, my last eye test was January, so I went back to the optician who sent me to eye casualty. Hydroxychloroquine and macular degeneration - NRAS. Hydroxychloroquine toxicity - EyeWiki. Plaquenil Side Effects on Your Eyes and Vision. Uncontrolled eye movements; unsteadiness, trembling, or other problems with muscle control or coordination; vomiting; For Healthcare Professionals. Applies to hydroxychloroquine compounding powder, oral tablet. Cardiovascular. Frequency not reported Cardiomyopathy can result in fatal cardiac failure, biventricular hypertrophy. Dermatologic Obtain a baseline eye exam within the first year of starting hydroxychloroquine to document any complicating eye problem. Annual screening beginning after 5 years of use. Sooner if there are major risk factors. Check the dose of hydroxychloroquine based on your weight at your doctor’s appointment. Hearing problems, such as ringing or ticking in the ears, or hearing changes Plaquenil may have toxic effects on your inner ear Loss of balance, coordination, room spinning, or other vertigo.