Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Hydroxychloroquine toxicity retina Plaquenil cause disufl The goal with ocular screening for the side effects of Plaquenil is to find the damage at the earliest stage to reduce the amount of vision loss. The risk is low in the beginning and increases over time as the drug collects in the retinal pigment epithelial layer. The risk of damage is dose related. PLAQUENIL can prolong the PR, QRS and QTc intervals, especially in patients with underlying risk factors. Serious adverse events, including fatal outcomes, have been reported in patients taking PLAQUENIL including ventricular arrhythmias, heart blocks, ventricular fibrillation and Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. Rarely, hydroxychloroquine can lead to anemia in some individuals. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil serious side effects Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus, Plaquenil Hydroxychloroquine Sulfate - Sanofi Plaquenil toxicity visual field Jan 18, 2019 One of the most significant side effects of the drug is its possibility of causing eye problems resulting in blurred or decreased vision. The most common issue is damage to the retina. It can impair your color vision or damage the retinal cells particularly in the area right around the central vision. What can Hydroxychloroquine Plaquenil do to my eyes?. Hydroxychloroquine Plaquenil. Plaquenil Indications, Side Effects, Warnings -. Check with your doctor immediately if any of the following side effects occur Incidence not known. Blistering, peeling, loosening of the skin blurred vision or other vision changes chest discomfort, pain, or tightness cough or hoarseness dark urine decreased urination defective color vision diarrhea difficulty breathing Sep 13, 2019 For the Consumer. Continuing ringing or buzzing or other unexplained noise in the ears. feeling of constant movement of self or surroundings. irritability. nausea. nervousness. nightmares. sensation of spinning. shakiness and unsteady walk. uncontrolled eye movements. unsteadiness, trembling, or. Serious side effects and their symptoms can include the following blurred vision or other vision changes. ringing in your ears or hearing loss. angioedema, or rapid swelling of your skin. hives. mild or severe bronchospasm that causes trouble breathing. sore throat. unusual bleeding or.