It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Hydroxychloroquine and chloroquine Side effects of plaquenil for lupus Macular degeneration plaquenil Plaquenil toxicity bull's eye maculopathy Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use. One of the most significant side effects of the drug is its possibility of causing eye problems resulting in blurred or decreased vision. The most common issue is damage to the retina. It can impair your color vision or damage the retinal cells particularly in the area right around the central vision. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil eye side effect Hydroxychloroquine Plaquenil, Rx Side Effects New Plaquenil Guidelines and More. Does plaquenil affect cgrp inhibitors Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Side effects, drug interactions, pregnancy safety information, and dosage information should be reviewed prior to taking this medication. Hydroxychloroquine Plaquenil Side Effects & Dosage for.. What can Hydroxychloroquine Plaquenil do to my eyes?. Conditions Plaquenil-related Eye Problems Eugene Eye Care. There are a number of other much less important side effects of Plaquenil, including changes in the cornea and changes in the eyelids. To be at risk of eye problems from Plaquenil you need to be on quite a high dose. The dose that you can safely tolerate depends on your size. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. While side effects of corticosteroids are usually to blame, there is also the possibility of ocular damage associated with long-term use of the antimalarial drugs hydroxychloroquine brand name Plaquenil® and chloroquine. Improved vision screening tests and updated dosing guidelines are key to avoiding such complications.