It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Plaquenil sulfate allergy Chloroquine base lethal dose Do not exceed 600 mg or 6.5 mg/kg 5 mg/kg base per day, whichever is lower, as the incidence of retinopathy has been reported to be higher when this maintenance dose is exceeded. Corticosteroids and salicylates may be used in conjunction with PLAQUENIL, and they can generally be decreased gradually in dosage or eliminated after a maintenance. Medscape - Indication-specific dosing for Plaquenil hydroxychloroquine sulfate, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Rheumatoid arthritis is a chronic disorder for which there is no known cure. Fortunately in the last few years, a shift in strategy toward the earlier institution of disease modifying drugs and the availability of new classes of medications have greatly improved the outcomes that can be expected by most patients. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil maintenance dosage Plaquenil and Maintenance - HealthBoards, Plaquenil hydroxychloroquine sulfate dosing, indications. Hydroxychloroquine interaction Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Plaquenil Uses, Dosage & Side Effects -. Rheumatoid Arthritis Treatment Options Johns Hopkins.. Plaquenil - FDA prescribing information, side effects and uses. The usual starting dose of Plaquenil is 200 mg twice a day or 400 mg once a day, administered orally, in people weighing 80 kg or more. The usual dosage works for most people who take Plaquenil, but it is possible to increase or decrease the dose based on individual needs. It's important to watch for possible side effects and toxicity. Any daily dose of greater than 400 mg and being prescribed a maintenance dose of more than 6.5 mg/kg/day may increase the likelihood 1. Duration of treatment Taking Plaquenil for more than 5 years and if the total amount taken by the patient reaches more than 1000 g may put the patient at risk for the toxicity 1. DMARD Side Effects and Use. Hydroxychloroquine and sulfasalazine are used for mild rheumatoid arthritis. They are not as powerful as other DMARDs, but they usually cause fewer side effects.